Cutaneous metastases of colorectal tumors: Report of two cases

Abstract

Synchronous and metachronous metastases of colorectal cancer on skin are rare but are associated with advanced stages of the disease and poor short-term prognosis. Signet cell adenocarcinoma and high-grade B-cell lymphoma are uncommon histological types of the tumors, accounting for less than 1% of the cases each.  We describe two cases; a high-grade B-cell lymphoma with metastases to skin, liver and stomach, and a patient with diagnosis of poorly differentiated, high-grade, signet ring cells adenocarcinoma who developed metachronous lesions in the colon, rectum, and skin. Metastases in colonic cancer are associated with poor short-term survival. Although the most common organ of appearance is the liver, the development of extracolonic lesions in rare locations such as skin is related to deeper compromise and worse prognosis.